Study to compare the effect of Dexmedetomidine vs MgSo4 (50%) intrathecally as an adjuvant with bupivacaine (0.5%) for lower limb orthopedic surgery under subarachnoid block

Lower limb surgeries may be performed under local, regional (spinal or epidural) general anesthesia, but neuraxial blockade is the preferred mode of anesthesia. Sub-arachnoid block Spinal anaesthesia most common central used in a surgical setting, which being versatile and commonly block. With increasing use hyperbaric bupivacaine for sub arachnoid block, their limitations like prolongation onset sensory motor blockage effect, short duration action early postoperative requirement an analgesic agent, require intrathecal adjuvant to these local anaesthetic agents complete satisfactory period patient satisfaction. The aim this study was compare evaluate effect Dexmedetomidine with MgSO4 (50%) intrathecally as characteristics lower orthopedic surgery subarachnoid along (0.5%). : Participants were randomly divided into two groups 40 participants each. Group D (n=40) received Bupivacaine + dexmedetomidine, M MgSO4. Under strict aseptic antiseptic precaution performed. Mixture drugs according group assign injected. Assessment done. Inj. spinal seems superior intra-thecal it has faster onset, longer action, prolonged analgesia comparison Magnesium Sulphate without significant hemodynamic alterations. Dexmedetomidine, intra-thecally sub-arachnoid Sulphate.